2-甲基-2-丙基(6-{2-[2-(4-氟苯基)-5-异丙基-3-苯基-4-(苯基氨基甲酰)-1H-吡咯-1-基]乙基}-2,2-二甲基-1,3-二恶烷-4-基)乙酸酯合成路线 （共 3 条）
反应条件
2,2,2-trimethylacetic acid in n-heptane; toluene 19 h; Heating;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 73, # 2 p. 229 - 246
反应条件
hydrogenchloride in tetrahydrofuran T=25°C; 6 h;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 73, # 2 p. 229 - 246
反应条件
1: With hydrogenchloride in acetonitrile T=20°C; 2: With sodium hydroxide in water; acetonitrile T=20°C; 3: With hydrogenchloride in water; acetonitrile pH=9.0 - 9.5; Product distribution / selectivity;
参考文献
WO2009/157005 A1, ;
Page/Page column 12-14; 18 ;
