反应条件
1.1: 86 percent / imidazole; DMAP / dimethylformamide / 7 h / 20 °C 2.1: 94 percent / DMAP; pyridine / 16 h / 20 °C 3.1: 98 percent / TBAF / tetrahydrofuran / 3 h / Heating 4.1: 72 percent / PCC / CH2Cl2 / 0.5 h / 20 °C 5.1: p-toluenesulfonylhydrazine; Na2SO4 / ethanol / 3.5 h / 100 °C 5.2: 14 percent / NaBH3CN; p-toluenesulfonic acid monohydrate / dimethylformamide; tetrahydrothiophene 1,1-dioxide / 1 h / 100 °C 6.1: 70 percent / K2CO3 / methanol / 13 h / 50 °C View Scheme
参考文献
Hiroya, Kou; Takahashi, Taisuke; Miura, Nobuhiko; Naganuma, Akira; Sakamoto, Takao
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 10 p. 3229 - 3236
