1,4,7-三氮杂环壬烷合成路线 (共 26 条)
反应条件
1: With sulfuric acid in water T=140°C; 20 h; 2: With sodium hydroxide in water; toluene 2 h; Heating;
参考文献
Kramer, Jurjen; Scholten, Arjen; Driessen, Willem L.; Reedijk, Jan
European Journal of Inorganic Chemistry, 2002 , # 6 p. 1488 - 1494
反应条件
palladium 10 on activated carbon; hydrogen; acetic acid
参考文献
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); UNIVERSITE DE BOURGOGNE; Denat, Franck; Desogere, Pauline; Bernhard, Claire; Rousselin, Yoann; Boschetti, Frederic
Patent: US2014/142298 A1, 2014 ;
Location in patent: Paragraph 0275; 0276 ;
反应条件
cesium fluoride in N,N-dimethyl-formamide T=95°C; 24 h;
参考文献
Hoye; Richman; Dantas; Lightbourne; Scott Shinneman
Journal of Organic Chemistry, 2001 , vol. 66, # 8 p. 2722 - 2725
反应条件
sodium hydroxide in water; toluene Heating;
参考文献
Stavila, Vitalie; Allali, Mustapha; Canaple, Laurence; Stortz, Yvon; Franc, Cecile; Maurin, Philippe; Beuf, Olivier; Dufay, Olivier; Samarut, Jacques; Janier, Marc; Hasserodt, Jens
New Journal of Chemistry, 2008 , vol. 32, # 3 p. 428 - 435
反应条件
potassium hydroxide in methanol
参考文献
Erhardt,J.M.; Grover,E.R.; Wuest,J.D.
Journal of the American Chemical Society, 1980 , vol. 102, p. 6365
反应条件
potassium hydroxide 1) toluene, 80-90 deg C, 2-3 h, 2) 80-90 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), , # 1 p. 83 - 90
反应条件
lithium hydroxide in ethanol; water 3 h; Heating;
参考文献
Lo, H. Christine; Chen, Hong; Fish, Richard H.
European Journal of Inorganic Chemistry, 2001 , # 9 p. 2217 - 2220
反应条件
in acetonitrile Yield given;
参考文献
Farrugia, Louis J.; Lovatt, Paul A.; Peacock, Robert D.
Journal of the Chemical Society - Dalton Transactions, 1997 , # 6 p. 911 - 912
反应条件
formic acid T=101°C;
参考文献
Chemical Communications, , vol. 46, # 10 p. 1640 - 1642
反应条件
n-butyllithium 1.) Et2O, -78 deg C 2.) r. t., 0.5 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 1 p. 137 - 146