1,4,7-三氮杂环壬烷合成路线 （共 26 条）
反应条件
1: With sodium hydride in tetrahydrofuran
T=20°C; 6 h;
2: With water in tetrahydrofuran
参考文献
Vidal, Laurent; Sabelle, Stephane; Ly-Carry, Thi-My
Patent: US2005/120494 A1, 2005 ;
Location in patent: Page/Page column 17 ;
反应条件
1: 90 percent / 3 h / 85 °C
2: 83 percent
3: 1.) H2O; 2.) aq. NaOH / 1.) reflux; 2.) reflux
View Scheme
参考文献
Weisman, Gary R.; Vachon, David J.; Johnson, Van B.; Gronbeck, Dana A.
Journal of the Chemical Society, Chemical Communications, 1987 , p. 886 - 887
参考文献
CONCAT LP, a California Limited Partnership
Patent: US2005/112066 A1, 2005 ;
Location in patent: Page/Page column 26 ;
反应条件
sodium hydroxide in water
3 h;
参考文献
De Vos, Dirk E.; Bein, Thomas
Journal of Organometallic Chemistry, 1996 , vol. 520, # 1-2 p. 195 - 200
反应条件
1.1: 85 percent / 5 h / Heating
2.1: 80 percent / acetonitrile / 12 h / 20 °C
3.1: H2O / 3 h / Heating
3.2: 74 percent / KOH / ethanol / 48 h / Heating
View Scheme
参考文献
Blake, Alexander J.; Danks, Jonathan P.; Li, Wan-Sheung; Lippolis, Vito; Schroeder, Martin
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 2000 , # 17 p. 3034 - 3040
反应条件
in water
10percent excess of amine ligand over Zn(NO3)2 in water;
参考文献
Shelton, Valerie M.; Morrow, Janet R.
Inorganic Chemistry, 1991 , vol. 30, p. 4295 - 4299
