butyl lithium in diethyl ether; hexane T=-78°C; 0.25 h;

1: 1,5-dibromo-2,4-difluorobenzene With n-butyllithium in diethyl ether; hexane T=-78°C; 0.5 h; 2: N,N-dimethyl-formamide in diethyl ether; hexane T=-78°C; 0.5 h; 3: With acetic acid in diethyl ether; hexane; water

1.1: bromine; iron / dichloromethane / 20 °C 2.1: n-butyllithium / diethyl ether / 0.5 h / -78 °C 2.2: 0.5 h / -78 °C View Scheme