5,24(28)-胆甾二烯-24-亚甲基-3beta-醇合成路线 （共 23 条）
反应条件
sodium hydride in 1,4-dioxane; dimethyl sulfoxide T=80°C; 2 h;
参考文献
Lu, Weigang; Zhang, Cuixian; Zeng, Longmei; Su, Jingyu
Steroids, 2004 , vol. 69, # 13-14 p. 803 - 808
反应条件
toluene-4-sulfonic acid in 1,4-dioxane; water T=80°C; 1 h;
参考文献
Back, Thomas G.; Proudfoot, John R.; Djerassi, Carl
Tetrahedron Letters, 1986 , vol. 27, # 20 p. 2187 - 2190
反应条件
sodium hydride; dimethyl sulfoxide T=80°C; 4 h;
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1.1: 88 percent / cc. HCl / 24 h / 20 °C 2.1: 76 percent / iodobenzene dibromide / 20 °C 3.1: O3 3.2: 62 percent / Zn; CH3COOH / 20 °C 4.1: 69 percent / K2CO3; formamide / acetonitrile / 9 h / 20 °C 5.1: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 6.1: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1: 69 percent / K2CO3; formamide / acetonitrile / 9 h / 20 °C 2: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 3: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1: 69 percent / K2CO3; formamide / acetonitrile / 9 h / 20 °C 2: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 3: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 2: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1.1: 76 percent / iodobenzene dibromide / 20 °C 2.1: O3 2.2: 62 percent / Zn; CH3COOH / 20 °C 3.1: 69 percent / K2CO3; formamide / acetonitrile / 9 h / 20 °C 4.1: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 5.1: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1.1: O3 1.2: 62 percent / Zn; CH3COOH / 20 °C 2.1: 69 percent / K2CO3; formamide / acetonitrile / 9 h / 20 °C 3.1: 98 percent / H2 / PtO2 / ethyl acetate / 0.5 h / 20 °C 4.1: 86 percent / NaH; DMSO / 4 h / 80 °C View Scheme
参考文献
Cui, Jian Guo; Lin, Cui Wu; Zeng, Long Mei; Su, Jing Yu
Steroids, 2002 , vol. 67, # 13-14 p. 1015 - 1019
反应条件
1: 80 percent / AIBN / benzene / 18 h / Heating 2: tetrahydrofuran / 0 deg C, 1-2 h then R.T., 1-2 h 3: Na/Hg, Na2HPO4 / tetrahydrofuran; methanol / 20 h / Ambient temperature 4: 67 percent / TsOH / dioxane; H2O / 1 h / 80 °C View Scheme
参考文献
Back, Thomas G.; Proudfoot, John R.; Djerassi, Carl
Tetrahedron Letters, 1986 , vol. 27, # 20 p. 2187 - 2190
