1’-苄基螺[吲哚啉-3,4’-哌啶]合成路线 (共 2 条)
反应条件
1: With trifluoroacetic acid in toluene; acetonitrile T=35°C; 2: With sodium tetrahydroborate in methanol; toluene; acetonitrile T=-10 - 20°C; 1 h; 3: With ammonia; water in methanol; toluene; acetonitrile
参考文献
WO2005/97794 A1, ;
Page/Page column 42 ;
WO 2005/097794 A1
反应条件
in dichloromethane
T=5 - 20°C; 8 h;
参考文献
JANSSEN PHARMACEUTICA N.V.
Patent: WO2005/97794 A1, 2005 ;
Location in patent: Page/Page column 43 ;
WO 2005/097794 A1