1: acetonitrile With lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 1 h; 2: 4-bromo-2-fluorophenyl ethyl carbonate in tetrahydrofuran T=-78 - 20°C; 16 h;

4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 20 h;