(4R)-3-[(2R)-2-甲基-1-氧代丁基]-4-(苯基甲基)-2-恶唑烷酮合成路线 （共 4 条）
反应条件
lithium borohydride in methanol; diethyl ether T=-20 - 0°C; 2 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 16, # 1 p. 26 - 29
反应条件
methanol; lithium borohydride in tetrahydrofuran T=0 - 20°C; 3 h;
参考文献
Yang, Zhicai; Jin, Xiaomin; Guaciaro, Michael; Molino, Bruce F.
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3191 - 3196
反应条件
lithium borohydride in methanol; diethyl ether T=-20 - 0°C; 2 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 16, # 1 p. 26 - 29
反应条件
<b>Multi-step reaction with 2 steps<br /> </b>1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere<br />1.2: -78 - 20 °C / |Inert atmosphere<br />2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / |Inert atmosphere<br />2.2: 2 h / -78 °C / |Inert atmosphere<br /> <br />
参考文献
Ding, Feiqing; William, Ronny; Leow, Min Li; Chai, Hua; Fong, Jacqueline Zi Mei; Liu, Xue-Wei Organic Letters, 2014 , vol. 16, # 1 p. 26 - 29
