1-BOC-4-氯吲哚-2-硼酸合成路线 （共 4 条）
反应条件
1: With tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran T=0 - 5°C; 0.5 h; 2: With hydrogenchloride in tetrahydrofuran Further stages.;
参考文献
Vazquez, Enrique; Davies, Ian W.; Payack, Joseph F.
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7551 - 7552
反应条件
lithium diisopropyl amide in tetrahydrofuran T=0 - 20°C; 1 h;
参考文献
SANOFI; ARNAUD, Joëlle; ARTIAGA, Martine; BARTH, Francis; HORTALA, Laurent; MARTINEZ, Serge; ROUX, Pascale
Patent: WO2013/87643 A1, 2013 ;
Location in patent: Page/Page column 18 ;
反应条件
1.1: DMAP / CH2Cl2 / 0.75 h / 20 °C 2.1: (iPrO)3B; LDA / tetrahydrofuran / 0.5 h / 0 - 5 °C 2.2: 99 percent / 2N HCl / tetrahydrofuran View Scheme
参考文献
SANOFI; ARNAUD, Joëlle; ARTIAGA, Martine; BARTH, Francis; HORTALA, Laurent; MARTINEZ, Serge; ROUX, Pascale
Patent: WO2013/87643 A1, 2013 ;
反应条件
1.1: DMAP / CH2Cl2 / 0.75 h / 20 °C 2.1: (iPrO)3B; LDA / tetrahydrofuran / 0.5 h / 0 - 5 °C 2.2: 99 percent / 2N HCl / tetrahydrofuran View Scheme
参考文献
SANOFI; ARNAUD, Joëlle; ARTIAGA, Martine; BARTH, Francis; HORTALA, Laurent; MARTINEZ, Serge; ROUX, Pascale
Patent: WO2013/87643 A1, 2013 ;
