1-Boc-5-氰基吲哚-2-硼酸合成路线 （共 4 条）
反应条件
1: With tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran T=0°C; 2 h; 2: With phosphate buffer in tetrahydrofuran pH=6.0; Further stages.;
参考文献
Mizuta, Masahiro; Seio, Kohji; Miyata, Kenichi; Sekine, Mitsuo
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5046 - 5055
反应条件
tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran; cyclohexane T=0 - 20°C; 2.33333 h;
参考文献
Aventis Pharma S.A.
Patent: US2004/242559 A1, 2004 ;
Location in patent: Page 19 ;
US 20040242559 A1
反应条件
1.1: 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 1 h / 20 °C 2.1: triisopropyl borate; LDA / tetrahydrofuran / 2 h / 0 °C 2.2: 82 percent / aq. phosphate buffer / tetrahydrofuran / pH 6.0 View Scheme
参考文献
Vazquez, Enrique; Davies, Ian W.; Payack, Joseph F.
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7551 - 7552
反应条件
1.1: 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 1 h / 20 °C 2.1: triisopropyl borate; LDA / tetrahydrofuran / 2 h / 0 °C 2.2: 82 percent / aq. phosphate buffer / tetrahydrofuran / pH 6.0 View Scheme
参考文献
Vazquez, Enrique; Davies, Ian W.; Payack, Joseph F.
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7551 - 7552
