2,2',3,3',4',6,6'-七-O-乙酰基-alpha-D-乳糖基溴化物合成路线 （共 37 条）
反应条件
1: 57 percent / tetrabutylammonium hydrogen sulphate (TBAHS), 1 M aq. NaOH / CH2Cl2 / 25 °C 2: 100 percent / NaOMe / methanol 3: ammonium formate / 10percent Pd/C / methanol / 0.08 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 7 p. 536 - 538
反应条件
β-cyclodextrin; zinc in water T=20°C; 1.5 h; Sonication;
参考文献
Zhao, Jinzhong; Shao, Huawu; Wu, Xin; Shi, Shaojing
Chinese Journal of Chemistry, 2011 , vol. 29, # 7 p. 1434 - 1440
反应条件
1: 1.) HgO, HgBr2, CaSO4, 2.) HgBr2 / 1.) CHCl3, 20 h, 2.) toluene, nitromethane, 50 deg C, 24 h 2: BF3*Et2O / toluene / 3 h / 22 °C View Scheme
参考文献
Jansson, Karl; Ahlfors, Stefan; Frejd, Torbjoern; Kihlberg, Jan; Magnusson, Goeran; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5629 - 5647
反应条件
silver imidazolate; 3 A molecular sieve; zinc(II) chloride in dichloromethane T=40°C; 48 h;
参考文献
Patil, Premanand Ramrao; Ravindranathan Kartha
Journal of Carbohydrate Chemistry, 2008 , vol. 27, # 7 p. 411 - 419
参考文献
Nakamura, Motomi; Tsutsumi, Mayuka; Ishikawa, Yoshiaki; Umemiya, Haruka; Izawa, Kazumi; Abe, Haruka; Togashi, Yosuke; Kinone, Tatsuya; Sekiguchi, Sho; Igumi, Mihiro; Ide, Kanako; Hasegawa, Teruaki; Hasegawa, Toki
Tetrahedron, 2013 , vol. 69, # 14 p. 3019 - 3026
反应条件
1: 1.) HgO, HgBr2, CaSO4, 2.) HgBr2 / 1.) CHCl3, 20 h, 2.) toluene, nitromethane, 50 deg C, 24 h 2: BF3*Et2O / toluene / 3 h / 22 °C View Scheme
参考文献
Jansson, Karl; Ahlfors, Stefan; Frejd, Torbjoern; Kihlberg, Jan; Magnusson, Goeran; et al.
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5629 - 5647
反应条件
mercury(II) cyanide in nitromethane; benzene T=40°C; 4 h;
参考文献
Hronowski, Lucjan J. J.; Szarek, Walter A.; Hay, George W.; Ison, Edward R.; Krebs, Anita; Depew, William T.
Carbohydrate Research, 1991 , vol. 219, # 1 p. 51 - 69
反应条件
1: 81 percent / Bu4NBr, 2,4,6-trimethylpyridine / 10 h / 50 °C 2: 1) 88percent HCOOH, 2) Ag2O / 1) rt, 15 min, 2) DMF, ice-bath, 1.5 h, rt, 6 h View Scheme
参考文献
Hronowski, Lucjan J. J.; Szarek, Walter A.; Hay, George W.; Ison, Edward R.; Krebs, Anita; Depew, William T.
Carbohydrate Research, 1991 , vol. 219, # 1 p. 51 - 69
反应条件
1: 96 percent / NaN3; aq. NaHCO3; Bu4NHSO4 / CH2Cl2 / 2 h / 20 °C 2: 97 percent / NaOMe / methanol / 20 °C View Scheme
参考文献
Zhang, Wei; Wang, Jianqiang; Li, Jun; Yu, Libing; Wang, Peng George
Journal of Carbohydrate Chemistry, 1999 , vol. 18, # 8 p. 1009 - 1017
反应条件
1.1: AgClO4; 4 Angstroem molecular sieves; Ag2CO3 / 24 h / 20 °C 1.2: aq. TFA / CH2Cl2 2.1: 99 percent / Na / methanol / 1 h / 20 °C View Scheme
参考文献
Turnbull, W.Bruce; Harrison, Jennifer A; Ravindranathan Kartha; Schenkman, Sergio; Field, Robert A
Tetrahedron, 2002 , vol. 58, # 16 p. 3207 - 3216
