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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
4753-09-7
合成路线
(共 20 条)
4753-09-7
→
反应条件
3790-45-2
1-苯基-2,3,4,9-四氢-1H-beta-咔啉
反应条件
1: phosphorus oxychloride 2: sodium borohydride View Scheme
参考文献
Espinoza-Moraga, Marlene; Caballero, Julio; Gaube, Friedemann; Winckler, Thomas; Santos, Leonardo S.
Chemical Biology and Drug Design, 2012 , vol. 79, # 4 p. 594 - 599
4753-09-7
→
反应条件
61-54-1
色胺
反应条件
sodium hydroxide in water; ethylene glycol
参考文献
Shono, Tatsuya; Matsumura, Yoshihiro; Kanazawa, Takenobu
Tetrahedron Letters, 1983 , vol. 24, # 12 p. 1259 - 1262
4753-09-7
→
反应条件
10022-79-4
反应条件
trichlorophosphate in benzene Bischler-Napieralski reaction; Reflux;
参考文献
Espinoza-Moraga, Marlene; Caballero, Julio; Gaube, Friedemann; Winckler, Thomas; Santos, Leonardo S.
Chemical Biology and Drug Design, 2012 , vol. 79, # 4 p. 594 - 599
4753-09-7
→
反应条件
10022-75-0
反应条件
Lawesson's reagent in ethylene glycol dimethyl ether 3 h; Ambient temperature;
参考文献
Ishida; Nakamura; Irie; Oh-Ishi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3237 - 3249
61-54-1
色胺
+
65-85-0
苯甲酸
→
反应条件
4753-09-7
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 12 h;
参考文献
Espinoza-Moraga, Marlene; Caballero, Julio; Gaube, Friedemann; Winckler, Thomas; Santos, Leonardo S.
Chemical Biology and Drug Design, 2012 , vol. 79, # 4 p. 594 - 599
61-54-1
色胺
+
13665-04-8
2,2-二溴-1-苯乙酮
→
反应条件
4753-09-7
反应条件
1: α,α-dibromo-1-phenylethanone With sodium iodide in dimethyl sulfoxide T=25 - 45°C; Inert atmosphere; 2: tryptamine With triethylamine in dimethyl sulfoxide T=25 - 45°C; Inert atmosphere; 3: With alpha,alpha-dimethylbenzyl hydroperoxide in hexane; dimethyl sulfoxide T=25 - 45°C; Inert atmosphere;
参考文献
Meruva, Suresh Babu; Raghunadh, Akula; Kamaraju, Raghavendra Rao; Kumar, U.K. Syam; Dubey
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 471 - 480
61-54-1
色胺
+
98-88-4
苯甲酰氯
→
反应条件
4753-09-7
反应条件
sodium hydroxide in acetone T=-30°C;
参考文献
Czerwinski, Kevin M.; Zificsak, Craig A.; Stevens, John; Oberbeck, Melissa; Randlett, Christopher; King, Melissa; Mennen, Steve
Synthetic Communications, 2003 , vol. 33, # 7 p. 1225 - 1231
126920-23-8
→
反应条件
4753-09-7
+
126920-25-0
反应条件
ammonium formate; palladium on activated charcoal in methanol 4.5 h; Heating;
参考文献
Kiguchi, Toshiko; Kuninobu, Naoko; Takahashi, Yoshiko; Yoshida, Yukiyo; Naito, Takeaki; Ninomiya, Ichiya
Synthesis, 1989 , # 10 p. 778 - 781
61-54-1
色胺
+
100-52-7
苯甲醛
→
反应条件
4753-09-7
反应条件
potassium phosphate; [Rh(trop2NH)(PPh3)]+(CF3SO2)-; methacrylic acid methyl ester in tetrahydrofuran T=0°C; 4 h;
参考文献
Rodriguez-Lugo, Rafael E.; Trincado, Monica; Gruetzmacher, Hansjoerg
ChemCatChem, 2013 , vol. 5, # 5 p. 1079 - 1083
343-94-2
色胺盐酸盐
+
98-88-4
苯甲酰氯
→
反应条件
4753-09-7
反应条件
potassium carbonate in water; ethyl acetate 1 h; Ambient temperature;
参考文献
Yoshioka, Tadao; Mohri, Kunihiko; Oikawa, Yuji; Yonemitsu, Osamu
Journal of Chemical Research, Miniprint, 1981 , # 7 p. 2252 - 2281
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