反应条件
1: 1.) NaH / 1.) HMPA, 0 deg C, 1 h, 2.) 20 min 2: 1.) ethylmagnesium bromide / 1.) THF, room temperature, 1 h, 2.) 15 min 3: 75 percent / DIBAH / tetrahydrofuran; toluene / 0.5 h / -78 °C 4: 90 percent / H2 / Lindlar catalyst / methanol / 24 h 5: 80 percent / imidazole / dimethylformamide / 18 h / Ambient temperature 6: 90 percent / LiAlH4, TiCl3 / tetrahydrofuran / 0.5 h / Ambient temperature 7: sodium fluoride, pyridinium fluoride / tetrahydrofuran; acetonitrile / 5 h / Ambient temperature 8: MnO2 / CCl4 / 0.5 h 9: 60 percent / NaCN, AgO, MnO2 / 14 h / 40 °C 10: 70 percent / 6 M NaOH / ethanol / 50 °C View Scheme
参考文献
Solladie; Girardin; Metra
Tetrahedron Letters, 1988 , vol. 29, # 2 p. 209 - 212
