异维 A 酸合成路线

110848-62-92-[[(2Z,4E,6E,8E)-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酰基]氨基]乙酸

参考文献

Shealy; Frye; Schiff
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 190 - 196

16760-45-5甲基(2Z,4E,6Z,8Z)-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酸酯

参考文献

Patel, Jyoti B.; Huynh, Carlic K.; Handratta, Venkatesh D.; Gediya, Lalji K.; Brodie, Angela M. H.; Goloubeva, Olga G.; Clement, Omoshile O.; Nanne, Ivo P.; Soprano, Dianne Robert; Njar, Vincent C. O.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6716 - 6729

4759-48-2异维 A 酸

16760-45-5甲基(2Z,4E,6Z,8Z)-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酸酯

参考文献

Finkelshtein; Krasnokutskaya
Journal of Physical Organic Chemistry, 1996 , vol. 9, # 6 p. 411 - 418

186581-53-3重氮甲烷+

4759-48-2异维 A 酸

16760-45-5甲基(2Z,4E,6Z,8Z)-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酸酯

参考文献

Curley, Robert W.; Fowble, John W.
Magnetic Resonance in Chemistry, 1989 , vol. 27, # 7 p. 707 - 709

4759-48-2异维 A 酸

75686-04-3(2Z,4E,6E,8E)-N-乙基-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯基)壬-2,4,6,8-四烯酰胺

参考文献

Shealy; Frye; O'Dell; Thorpe; Kirk; Coburn Jr.; Sporn
Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 6 p. 745 - 751

4759-48-2异维 A 酸+

123-30-8对氨基苯酚

75686-07-613-顺式-芬维A胺

参考文献

Campos-Sandoval, Jose Angel; Redondo, Clara; Kinsella, Gemma K.; Pal, Akos; Jones, Geraint; Eyre, Gwen S.; Hirst, Simon C.; Findlay, John B. C.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4378 - 4387

4759-48-2异维 A 酸

75686-07-613-顺式-芬维A胺

参考文献

Shealy; Frye; O'Dell; Thorpe; Kirk; Coburn Jr.; Sporn
Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 6 p. 745 - 751

13325-10-54-氨基-1-丁醇+

4759-48-2异维 A 酸

84680-31-9

参考文献

Shealy; Frye; O'Dell; Thorpe; Kirk; Coburn Jr.; Sporn
Journal of Pharmaceutical Sciences, 1984 , vol. 73, # 6 p. 745 - 751