2-(氯甲基)-1-甲基-1H-苯并咪唑合成路线 （共 17 条）
反应条件
1: 140 - 150 °C 2: SOCl2 View Scheme
参考文献
Mamalis et al.
Journal of the Chemical Society, 1950 , p. 1600,1602
反应条件
ammonium hydroxide; sodium hydroxide; sodium carbonate; formamide in 1,4-dioxane 3 h;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 29, # 5 p. 567 - 574
Khimiya Geterotsiklicheskikh Soedinenii, , # 5 p. 664 - 672
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in water; N,N-dimethyl-formamide 3 h;
参考文献
Popov, I. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1993 , vol. 29, # 5 p. 567 - 574
Khimiya Geterotsiklicheskikh Soedinenii, 1993 , # 5 p. 664 - 672
反应条件
1: K2CO3 / acetone 2: 40 percent / Hg2Cl2, Al foil / diethyl ether View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, p. 578 - 579
反应条件
in ethanol T=0°C; 0.75 h;
参考文献
Butera, John A.; Spinelli, Walter; Anantharaman, Viji; Marcopulos, Nicholas; Parsons, Roderick W.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3212 - 3228
反应条件
potassium carbonate in ethyl acetate
3 h; Heating;
参考文献
Wilson; Hunt
Australian Journal of Chemistry, 1983 , vol. 36, # 11 p. 2317 - 2325
反应条件
ueber <1-Methyl-1H-benzimidazol-2-ylmethylimino>-di-essigsaeure-dimethylester;
参考文献
Irving; Weber
Journal of the Chemical Society, 1959 , p. 2296
