(4aR,7aR)-4A-乙氧基-2,2-二甲基四氢-6H-呋喃并[3,2-d][1,3]二恶英-6-酮合成路线 （共 6 条）
反应条件
4 A molecular sieve; toluene-4-sulfonic acid in benzene
0.5 h; Heating;
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
反应条件
1: 50 percent / KMnO4; DCH-18-crown-6 / CH2Cl2
2: 96 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
3: 92 percent / ethylene glycol; SmI2 / tetrahydrofuran / 0.5 h / 20 °C
4: 100 percent / H2 / 10percent Pd/C / ethanol / 1 h / 760.05 Torr
5: 59 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
View Scheme
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
反应条件
1: 96 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
2: 92 percent / ethylene glycol; SmI2 / tetrahydrofuran / 0.5 h / 20 °C
3: 100 percent / H2 / 10percent Pd/C / ethanol / 1 h / 760.05 Torr
4: 59 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
View Scheme
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
反应条件
1: 92 percent / ethylene glycol; SmI2 / tetrahydrofuran / 0.5 h / 20 °C
2: 100 percent / H2 / 10percent Pd/C / ethanol / 1 h / 760.05 Torr
3: 59 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
View Scheme
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
反应条件
1: 100 percent / H2 / 10percent Pd/C / ethanol / 1 h / 760.05 Torr
2: 59 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
View Scheme
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
反应条件
1: 95 percent / TBAF
2: 50 percent / KMnO4; DCH-18-crown-6 / CH2Cl2
3: 96 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
4: 92 percent / ethylene glycol; SmI2 / tetrahydrofuran / 0.5 h / 20 °C
5: 100 percent / H2 / 10percent Pd/C / ethanol / 1 h / 760.05 Torr
6: 59 percent / 4 Angstroem molecular sieves; TsOH / benzene / 0.5 h / Heating
View Scheme
参考文献
Hegedus, Louis S.; Geisler, Lisa; Riches, Andrew G.; Salman, Sarri S.; Umbricht, Gisela
Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7649 - 7655
