4-(氯甲基)-2-苯基-1,3-噻唑合成路线 （共 21 条）
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: ethanol 2: aqueous HCl View Scheme
参考文献
Huntress; Pfister
Journal of the American Chemical Society, 1943 , vol. 65, p. 1667,1669
反应条件
sodium hydrogencarbonate; dimethyl sulfoxide T=130°C; Oxidation; 1 h;
参考文献
Einsiedel, Juergen; Thomas, Christoph; Huebner, Harald; Gmeiner, Peter
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 17 p. 2041 - 2044
参考文献
Angyal et al.
Journal of the Chemical Society, 1953 , p. 1740
参考文献
Mahmoodi, Majid; Aliabadi, Alireza; Emami, Saeed; Safavi, Maliheh; Rajabalian, Saeed; Mohagheghi, Mohammad-Ali; Khoshzaban, Ahad; Samzadeh-Kermani, Alireza; Lamei, Navid; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2010 , vol. 343, # 7 p. 411 - 416
反应条件
sodium hydroxide; NaH in ethanol; water; N,N-dimethyl-formamide
参考文献
John Wyeth and Brother
Patent: US3979402 A1, 1976 ;
反应条件
(i) KOH, DMF, (ii) /BRN= 142544/; Multistep reaction;
参考文献
Postescu,I.D.; Csavassy,G.
Journal fuer Praktische Chemie (Leipzig), 1977 , vol. 319, p. 347 - 352
反应条件
1: dimethylformamide
2: HCl, BF3-Et2O
3: Et3N
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: dimethylformamide
2: HCl, BF3-Et2O
3: Et3N
4: aq. NaOH / ethanol
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: dimethylformamide
2: HCl, BF3-Et2O
3: Et3N
4: aq. NaOH / ethanol
5: K2CO3 / acetone
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
