2: Ph3P / benzene / 135 °C 3: aq. EtOH 4: nBuLi View Scheme

1: benzene 2: nBu3P 3: H2O View Scheme

1: benzene 2: nBu3P View Scheme

1.1: pyridine / dichloromethane / 24.5 h / 0 - 25 °C 2.1: N,N,N',N,-tetramethylethylenediamine; sodium carbonate; copper(l) chloride / acetonitrile / 16 h / 30 °C / Inert atmosphere 2.2: Inert atmosphere View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3571227', constants.ctx, '0')">tetrabutyl-ammonium chloride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587218', constants.ctx, '0')">oxygen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3902968', constants.ctx, '0')">chlorine</a> <br />T=120 - 125&deg;C;&nbsp;10&nbsp;h;&nbsp;&nbsp;DarknessNeat (no solvent);&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: LiOH / propan-2-ol; H₂O / 0.25 h / -7 &deg;C<br />2: oxalyl chloride, DMF / CH₂Cl₂ / 20 - 40 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2036449', constants.ctx, '0')">phosphorus pentachloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098295', constants.ctx, '0')">tetrachloromethane</a> <br />&nbsp;Heating;&nbsp;<br /> &nbsp;