2,6-二氯吡嗪合成路线

参考文献

Seeman, Jeffey I.; Paine III, John B.; Secor, Henry V.; Im, Hoong-Sun; Bernstein
Journal of the American Chemical Society, 1992 , vol. 114, # 13 p. 5269 - 5280

4774-14-52,6-二氯吡嗪+

98-80-6苯硼酸

25827-94-5

参考文献

Schultheiss, Nate; Bosch, Eric
Heterocycles, 2003 , vol. 60, # 8 p. 1891 - 1897

4774-14-52,6-二氯吡嗪+

5720-07-04-甲氧基苯硼酸

850221-79-32-氯-6-(4-甲氧基-苯基)-吡嗪

参考文献

Buron, Frederic; Ple, Nelly; Turck, Alain; Queguiner, Guy
Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2616 - 2621

4774-14-52,6-二氯吡嗪+

78887-39-53-乙酰胺基苯硼酸

874143-25-6N-[3-(6-氯-吡嗪-2-基)-苯基]-乙酰胺

参考文献

THE WELLCOME TRUST LIMITED
Patent: US2008/15191 A1, 2008 ;
Location in patent: Page/Page column 67 ;

4774-14-52,6-二氯吡嗪+

74-88-4甲基碘

89284-38-83,5-二氯-2-甲基-吡嗪

参考文献

Termin, Andreas; Grootenhuis, Peter D.J.; Wilson, Dean M.; Molteni, Valentina; Mao, Long; Castellino, Angelo; Yang, Zhicai; Pechulis, Anthony; Suto, Mark
Patent: US2003/229091 A1, 2003 ;
Location in patent: Page 17 ;
US 20030229091 A1

372-20-33-氟苯酚+

4774-14-52,6-二氯吡嗪

894416-95-62-氯-6-(3-氟苯氧基)吡嗪

参考文献

Niculescu-Duvaz, Ion; Roman, Esteban; Whittaker, Steven R.; Friedlos, Frank; Kirk, Ruth; Scanlon, Ian J.; Davies, Lawrence C.; Niculescu-Duvaz, Dan; Marais, Richard; Springer, Caroline J.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 11 p. 3261 - 3274

4774-14-52,6-二氯吡嗪+

105-53-3丙二酸二乙酯

930798-26-82-(6-氯吡嗪-2-基)丙二酸二甲酯盐酸盐

参考文献

ASTRAZENECA AB
Patent: WO2007/35154 A1, 2007 ;
Location in patent: Page/Page column 28-29 ;
WO 2007/035154 A1

4774-14-52,6-二氯吡嗪+

100-46-9苄胺

426829-61-0

参考文献

Niculescu-Duvaz, Ion; Roman, Esteban; Whittaker, Steven R.; Friedlos, Frank; Kirk, Ruth; Scanlon, Ian J.; Davies, Lawrence C.; Niculescu-Duvaz, Dan; Marais, Richard; Springer, Caroline J.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 1 p. 407 - 416

1453-58-3+

4774-14-52,6-二氯吡嗪

612820-39-0

参考文献

Elhaik, Jerome; Money, Victoria A.; Barrett, Simon A.; Kilner, Colin A.; Evans, Ivana Radosavljevic; Halcrow, Malcolm A.
Dalton Transactions, 2003 , # 10 p. 2053 - 2060

4774-14-52,6-二氯吡嗪

61655-70-7

参考文献

The Dow Chemical Company
Patent: US4101546 A1, 1978 ;