3-氧代环戊基氨基甲酸叔丁酯合成路线 （共 4 条）
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide in dichloromethane
T=-78°C; 6.16 h;
2: With triethylamine in dichloromethane
T=-78°C;
参考文献
MERCK and CO., INC.; SUNESIS PHARMACEUTICALS, INC.
Patent: WO2007/11810 A1, 2007 ;
Location in patent: Page/Page column 29-30 ;
WO 2007/011810 A1
反应条件
1: methanol
2: TPAP; NMO / CH2Cl2
View Scheme
参考文献
Sheppeck II, James E.; Gilmore, John L.; Yang, Anle; Chen, Xiao-Tao; Xue, Chu-Biao; Roderick, John; Liu, Rui-Qin; Covington, Maryanne B.; Decicco, Carl P.; Duan, James J.-W.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 5 p. 1413 - 1417
反应条件
1: methanol
2: TPAP; NMO / CH2Cl2
View Scheme
参考文献
Sheppeck II, James E.; Gilmore, John L.; Yang, Anle; Chen, Xiao-Tao; Xue, Chu-Biao; Roderick, John; Liu, Rui-Qin; Covington, Maryanne B.; Decicco, Carl P.; Duan, James J.-W.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 5 p. 1413 - 1417
反应条件
diethylamino-sulfur trifluoride in 1,2-dichloro-ethane
T=60°C;
参考文献
MERCK and CO., INC.; SUNESIS PHARMACEUTICALS, INC.
Patent: WO2007/11810 A1, 2007 ;
Location in patent: Page/Page column 29-30 ;
WO 2007/011810 A1
