(6-异丙基-2-甲氧基吡啶-3-基)硼酸合成路线 (共 1 条)
反应条件
1: 2-isopropyl-6-methoxypyridine With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in diethyl ether
T=-60 - 20°C; 3.66667 h;
2: tri-isopropoxy-borane in diethyl ether
T=-60°C; 24 h;
3: With hydrogenchloride in diethyl ether; water
参考文献
NEUROGEN CORPORATION; AVENTIS PHARMACEUTICALS INC.
Patent: WO2005/23806 A2, 2005 ;
Location in patent: Page/Page column 56-57 ;
WO 2005/023806 A2