2,6-二溴-4-碘吡啶-3-醇合成路线 （共 2 条）
反应条件
1: With iodine; sodium hydrogencarbonate in water
T=20°C; 120 h;
2: With hydrogenchloride in water
pH=2;
参考文献
Cambridge Enterprise Limited; Kapadnis, Prashant Bhimrao; Glen, Robert; Hiley, Robin; Bell, James; Spring, David
Patent: US2013/53372 A1, 2013 ;
Location in patent: Paragraph 0597; 0598; 0599 ;
反应条件
1.1: sodium hydroxide; bromine / water / 0 °C
1.2: pH 2
2.1: sodium hydrogencarbonate; iodine / water / 120 h / 20 °C
2.2: pH 2
View Scheme
参考文献
CAMBRIDGE ENTERPRISE LIMITED; GLEN, Robert; HILEY, Robin; BELL, James; SPRING, David; KAPADNIS, Prashant, Bhimrao
Patent: WO2011/98776 A1, 2011 ;
WO 2011/098776 A1
