噻吩并[3,2-c]吡啶-2-羧酸甲酯合成路线 (共 4 条)
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
T=45°C; 18 h;
参考文献
Pfizer Inc.
Patent: US2008/90861 A1, 2008 ;
Location in patent: Page/Page column 20 ;
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
T=45°C;
参考文献
HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: WO2011/79804 A1, 2011 ;
Location in patent: Page/Page column 26 ;
WO 2011/079804 A1
反应条件
hydrogenchloride; sodium hydroxide in methanol; water
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;