1: 2-picoline With n-butyllithium in tetrahydrofuran T=-78°C; 0.75 h; 2: 2,6-di-fluoro-pyridine in tetrahydrofuran 3 h; Heating;

1: 2,6-dimethylpyridine With n-butyllithium in diethyl ether; hexane T=20°C; 1 h; 2: pyridine in toluene T=110°C; 0.333333 h;