6-甲氧基-2-苯基喹啉合成路线 （共 28 条）
反应条件
1.1: trifluoromethanesulfonic anhydride; 2-chloropyridine / CH2Cl2 / -78 - 0 °C
1.2: 89 percent / CH2Cl2; tetrahydrofuran / -78 - 0 °C
2.1: 92 percent / ammonium hexafluorophosphate; 2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl / CpRuCl(PPh3)2 / toluene / 105 °C
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参考文献
Hill, Matthew D.; Movassaghi, Mohammad
Synthesis, 2007 , # 7 p. 1115 - 1119
反应条件
ytterbium(III) triflate in acetonitrile
1.5 h; Ambient temperature;
参考文献
Makioka; Shindo; Taniguchi; Takaki; Fujiwara
Synthesis, 1995 , # 7 p. 801 - 804
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in acetonitrile
T=25°C; 0.166667 h;
参考文献
Bortolotti; Leardini; Nanni; Zanardi
Tetrahedron, 1993 , vol. 49, # 44 p. 10157 - 10174
反应条件
oxygen; ytterbium(III) triflate in dimethyl sulfoxide
T=90°C; P=760.051 Torr; 16 h;
参考文献
Sueki, Shunsuke; Okamoto, Chiharu; Shimizu, Isao; Seto, Keisuke; Furukawa, Yukio
Bulletin of the Chemical Society of Japan, 2010 , vol. 83, # 4 p. 385 - 390
反应条件
iron(III) chloride; chloranil in acetonitrile
0.75 h; Heating;
参考文献
Leardini, Rino; Nanni, Daniele; Tundo, Antonio; Zanardi, Giuseppe; Ruggieri, Fabrizio
Journal of Organic Chemistry, 1992 , vol. 57, # 6 p. 1842 - 1848
反应条件
hydrogenchloride; Tetrahexylammonium bromide in water; toluene
T=80 - 90°C; modified Doebner-Miller reaction;
参考文献
Reynolds, Kristie A.; Young, David J.; Loughlin, Wendy A.
Synthesis, 2010 , # 21 art. no. P11410SS, p. 3645 - 3648
反应条件
1: 6-Methoxyquinoline With Iron (III) nitrate nonahydrate; dipotassium peroxodisulfate; trifluoroacetic acid in water
T=20°C; 0.166667 h; Schlenk technique;
2: 3,4,5-trimethoxyphenylboronic acid in water
T=50°C; 24 h; Schlenk technique; Overall yield = 63 percent;
参考文献
Deb, Arghya; Manna, Srimanta; Maji, Arun; Dutta, Uttam; Maiti, Debabrata
European Journal of Organic Chemistry, 2013 , # 24 p. 5251 - 5256
反应条件
zinc dibromide in chloroform
T=90 - 100°C; Diels-Alder reaction; 2 h;
参考文献
Koyama, Junko; Toyokuni, Izumi; Tagahara, Kiyoshi
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 7 p. 1038 - 1039
反应条件
boron trifluoride diethyl etherate in benzene
48 h; Heating;
参考文献
Kametani, Tetsuji; Takeda, Hajime; Suzuki, Yukio; Honda, Toshio
Synthetic Communications, 1985 , vol. 15, # 6 p. 499 - 506
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in acetonitrile
24 h; Heating;
参考文献
Bortolotti; Leardini; Nanni; Zanardi
Tetrahedron, 1993 , vol. 49, # 44 p. 10157 - 10174
