sulfuric acid in acetone 48 h; Heating;

2: 1.) N-chlorosuccinimide, dimethyl sulphide, 2.) Zn / 2.) acetic acid 3: 87 percent / dioxane 4: sodium metaperiodate 5: 5percent H2SO4-AcOH / tetrahydrofuran / 3 h / Heating 7: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 8: 1.) O3, 2.) Me2S 9: sulphamic acid, sodium chlorite 10: H2SO4 / acetone 11: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 12: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 87 percent / dioxane 2: sodium metaperiodate 3: 5percent H2SO4-AcOH / tetrahydrofuran / 3 h / Heating 5: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 6: 1.) O3, 2.) Me2S 7: sulphamic acid, sodium chlorite 8: H2SO4 / acetone 9: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 10: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 1.) N-chlorosuccinimide, dimethyl sulphide, 2.) Zn / 2.) acetic acid 2: 87 percent / dioxane 3: sodium metaperiodate 4: 5percent H2SO4-AcOH / tetrahydrofuran / 3 h / Heating 6: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 7: 1.) O3, 2.) Me2S 8: sulphamic acid, sodium chlorite 9: H2SO4 / acetone 10: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 11: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: sodium metaperiodate 2: 5percent H2SO4-AcOH / tetrahydrofuran / 3 h / Heating 4: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 5: 1.) O3, 2.) Me2S 6: sulphamic acid, sodium chlorite 7: H2SO4 / acetone 8: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 9: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 5percent H2SO4-AcOH / tetrahydrofuran / 3 h / Heating 3: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 4: 1.) O3, 2.) Me2S 5: sulphamic acid, sodium chlorite 6: H2SO4 / acetone 7: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 8: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 2: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 1.) H2, 5percent HCl, 2.) O3 / 1.) r.t., 4 d 2: 1.) O3, 2.) Me2S 3: sulphamic acid, sodium chlorite 4: H2SO4 / acetone 5: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 6: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: 1.) O3, 2.) Me2S 2: sulphamic acid, sodium chlorite 3: H2SO4 / acetone 4: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 5: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme

1: sulphamic acid, sodium chlorite 2: H2SO4 / acetone 3: 52 percent / AlCl3, Me2S / CH2Cl2 / -10 °C 4: 68 percent / 5percent HCl / acetone / 24 h / 55 °C View Scheme