5,6-二羟基-2-吲哚甲酸合成路线 （共 23 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=760 Torr; 6 h;
参考文献
Synthetic Communications, , vol. 17, # 15 p. 1815 - 1822
反应条件
boron tribromide in dichloromethane T=-78 - 20°C;
参考文献
ACS Medicinal Chemistry Letters, , vol. 3, # 7 p. 550 - 554
反应条件
sodium hydroxide; sodium hydrogencarbonate; potassium hexacyanoferrate(III) in water pH=13; 0.25 h;
参考文献
Chemical Physics Letters, , vol. 433, # 4-6 p. 355 - 359
反应条件
in water T=40°C; pH=5 - < 8; 2 h; Acidic conditions; Product distribution / selectivity;
参考文献
EP1820491 A1, ;
Page/Page column 12 ;
反应条件
air; phosphate buffer pH 7.0 T=25°C; 2.5 h; mushroom tyrosinase;
参考文献
Gazzetta Chimica Italiana, , vol. 123, # 4 p. 241 - 242
反应条件
potassium hydroxide; sulfuric acid; oxygen in water T=25°C; pH=5.5; 0.666667 h; Enzymatic reaction; Product distribution / selectivity;
参考文献
EP1820491 A1, ;
Page/Page column 11; 16 ;
反应条件
water; boron tribromide in dichloromethane T=-40°C; 4 h;
参考文献
Molecules, , vol. 11, # 12 p. 968 - 977
反应条件
1: sodium acetate buffer, cerric ammonium nitrate / 1.5 h / pH 6.0 2: 84 percent / H2 / Pd/C / ethyl acetate / 6 h / 760 Torr View Scheme
参考文献
Synthetic Communications, , vol. 17, # 15 p. 1815 - 1822
反应条件
1: sodium acetate buffer, zinc acetate / 0.08 h 2: 84 percent / H2 / Pd/C / ethyl acetate / 6 h / 760 Torr View Scheme
参考文献
Synthetic Communications, , vol. 17, # 15 p. 1815 - 1822
反应条件
1: copper(l) iodide; caesium carbonate / dimethyl sulfoxide / 80 °C 2: water; sodium hydroxide / ethanol / 20 °C 3: boron tribromide / dichloromethane / -78 - 20 °C View Scheme
参考文献
ACS Medicinal Chemistry Letters, , vol. 3, # 7 p. 550 - 554
