(R)-3-(对甲基苯基)-beta-丙氨酸合成路线 (共 8 条)
反应条件
CAL-B (lipase B from Candida antarctica); water in isopropyl alcohol T=60°C; 30 h;
参考文献
Forro, Eniko; Paal, Tihamer; Tasnadi, Gabor; Fueloep, Ferenc
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 7-8 p. 917 - 923
反应条件
lipase B from Candida antarctica (Novozym 435, CAL-B) in di-isopropyl ether T=60°C; 48 h;
参考文献
Park, Seongsoon; Forro, Enikoe; Grewal, Harjap; Fueloep, Ferenc; Kazlauskas, Romas J.
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 8 p. 986 - 995
反应条件
alanine racemase (accession number AE015451 range 4,245,041-4,246,270), cloned from the genome of Pseudomonas putida (KT2440); Taxus phenylalanine aminomutase enzyme in water; glycerol T=31°C; pH=8; 20 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Cox, Brad M.; Bilsborrow, Joshua B.; Walker, Kevin D.
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 6953 - 6959
反应条件
Taxus phenylalanine aminomutase enzyme in water T=31°C; pH=8; 20 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Cox, Brad M.; Bilsborrow, Joshua B.; Walker, Kevin D.
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 6953 - 6959
反应条件
phenylalanine aminomutase T=31°C; 2 h; Enzyme kinetics;
参考文献
Cox, Brad M.; Bilsborrow, Joshua B.; Walker, Kevin D.
Journal of Organic Chemistry, 2009 , vol. 74, # 18 p. 6953 - 6959
反应条件
ammonia T=25°C; pH=9; aq. bufferEnzymatic reaction; Kinetics; regioselective reaction;
参考文献
Wu, Bian; Szymanski, Wiktor; Wybenga, Gjalt G.; Heberling, Matthew M.; Bartsch, Sebastian; Dewildeman, Stefaan; Poelarends, Gerrit J.; Feringa, Ben L.; Dijkstra, Bauke W.; Janssen, Dick B.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 2 p. 482 - 486
反应条件
carbon dioxide; Taxus chinensis phenylalanine aminomutase; ammonia in water pH=10; Enzymatic reaction; Kinetics; optical yield given as percent eeenantioselective reaction;
参考文献
Szymanski, Wiktor; Wu, Bian; Weiner, Barbara; De Wildeman, Stefaan; Feringa, Ben L.; Janssen, Dick B.
Journal of Organic Chemistry, 2009 , vol. 74, # 23 p. 9152 - 9157
反应条件
recombinant His-tagged phenylalanine aminomutase from Taxus chinensis; glycerol T=31°C; pH=8.5; aq. phosphate bufferEnzymatic reaction; Kinetics; Reagent/catalyst;
参考文献
Feng, Lei; Wanninayake, Udayanga; Strom, Susan; Geiger, James; Walker, Kevin D.
Biochemistry, 2011 , vol. 50, # 14 p. 2919 - 2930