4-甲氧基-2-苯并呋喃-1(3H)-酮合成路线 （共 48 条）
反应条件
1: tin (II)-chloride; aqueous hydrochloric acid / Behandeln des Reaktionsprodukts mit wss. Natronlauge
2: aqueous sulfuric acid / ueber das Diazoniumsalz
3: aq. NaOH solution
View Scheme
参考文献
Tirouflet
Bulletin de la Societe Scientifique de Bretagne, 1951 , vol. 26, p. Sonderheft 5, S. 7, 96
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1952 , vol. 235, p. 962
反应条件
1: ethanolic KOH-solution / Erhitzen des Reaktionsprodukts mit wss. Salzsaeure
2: aqueous sulfuric acid / ueber das Diazoniumsalz
3: aq. NaOH solution
View Scheme
参考文献
Tirouflet
Bulletin de la Societe Scientifique de Bretagne, 1951 , vol. 26, p. Sonderheft 5, S. 7, 96
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1952 , vol. 235, p. 962
反应条件
N-bromosuccinmide; azobisisobutyronitrile in tetrachloromethane
T=80°C;
参考文献
MENEAR, Keith Allan; Javaid, Muhammad Hashim; Gomez, Sylvie; Hummersone, Marc Geoffrey; Lence, Carlos Fenandez; Martin, Niall Morrison Barr; Rudge, David Alan; Roberts, Craig Anthony; Blades, Kevin
Patent: US2009/192156 A1, 2009 ;
Location in patent: Page/Page column 64 ;
反应条件
air; lithium diisopropyl amide
1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h; Yield given. Multistep reaction;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
1: With lithium borohydride in tetrahydrofuran
T=0 - 20°C; 2.5 h; Heating / reflux;
2: With hydrogenchloride in tetrahydrofuran; water
T=20°C;
参考文献
Sankyo Company, Limited
Patent: EP1362856 A1, 2003 ;
Location in patent: Page/Page column 147 ;
反应条件
ethanol; dimethyl amine
Behandeln des Reaktionsprodukts mit CrO3 in Essigsaeure und anschliessend mit wss. HCl;
参考文献
Blair et al.
Journal of the Chemical Society, 1955 , p. 708,711
反应条件
air; lithium diisopropyl amide
1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h; Yield given. Multistep reaction;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
air; lithium diisopropyl amide
1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h; Yield given. Multistep reaction;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
