5-氯吲哚-2-羧酸乙酯合成路线 （共 37 条）
反应条件
toluene-4-sulfonic acid in benzene 5 h; Heating;
参考文献
Murakami, Yasuoki; Yokoyama, Yuusaku; Miura, Tomoko; Hirasawa, Hiroko; Kamimura, Yuuko; Izaki, Miyako
Heterocycles, 1984 , vol. 22, # 5 p. 1211 - 1216
反应条件
1: in toluene T=20°C; Wittig reaction; 2: With triphenylphosphine; [MoO2Cl2(dmf)2] in toluene 24 h; Heating; Further stages.;
参考文献
Sanz, Roberto; Escribano, Jaime; Pedrosa, Maria R.; Aguado, Rafael; Arnaiz, Francisco J.
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 4-5 p. 713 - 718
反应条件
copper(l) iodide; caesium carbonate in dimethyl sulfoxide T=50°C; 4 h; Inert atmosphere;
参考文献
Cai, Qian; Li, Zhengqiu; Wei, Jiajia; Ha, Chengyong; Pei, Duanqing; Ding, Ke
Chemical Communications, 2009 , # 48 p. 7581 - 7583
反应条件
aluminium trichloride in benzene T=0°C; 0.25 h;
参考文献
Murakami; Watanabe; Kobayashi
Synthesis, 1984 , vol. NO. 9, p. 738 - 740
反应条件
copper(I) oxide; caesium carbonate in 1-methyl-pyrrolidin-2-one T=100°C; 16 h; Inert atmosphereSealed tube;
参考文献
Zhu, Zhiqiang; Yuan, Jiangjun; Zhou, Yirong; Qin, Yang; Xu, Jingshi; Peng, Yiyuan
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 511 - 514
反应条件
tetrabutylammomium bromide; palladium diacetate; sodium hydrogencarbonate in acetonitrile T=80°C; Heck-Jeffery amination; 96 h; Inert atmosphere;
参考文献
McNulty, James; Keskar, Kunal
European Journal of Organic Chemistry, 2011 , # 34 p. 6902 - 6908
反应条件
copper(l) iodide in dimethyl sulfoxide T=50°C; 0.166667 h; Ionic liquidInert atmosphereMicrowave irradiationSealed tube;
参考文献
Gu, Lijun; Li, Xiangguang
Journal of the Brazilian Chemical Society, 2011 , vol. 22, # 11 p. 2036 - 2039
反应条件
copper(l) iodide; caesium carbonate in dimethyl sulfoxide T=80°C; 16 h; Inert atmosphere;
参考文献
Koenig, Stefan G.; Dankwardt, John W.; Liu, Yanbing; Zhao, Hang; Singh, Surendra P.
Tetrahedron Letters, 2010 , vol. 51, # 50 p. 6549 - 6551
反应条件
in PPA; ethanol; water
参考文献
Sterling Drug Inc.
Patent: US5017584 A1, 1991 ;
US 5017584 A
反应条件
in 1,2-dichloro-benzene T=150°C; 0.5 h; regioselective reaction;
参考文献
Heaner Iv, William L.; Gelbaum, Carol S.; Gelbaum, Leslie; Pollet, Pamela; Richman, Kent W.; Dubay, William; Butler, Jeffrey D.; Wells, Gregory; Liotta, Charles L.
RSC Advances, 2013 , vol. 3, # 32 p. 13232 - 13242
