2,4,6-三羟基苯乙酮一水合物合成路线 （共 215 条）
反应条件
1: 800 mg / K2CO3 / acetone / 5 h / Heating
2: 415 mg / K2CO3 / acetone / 3 h / Heating
3: 350 mg / ethanol; aq. NaOH / 80 h / Ambient temperature
4: 200 mg / SeO2 / pentan-1-ol
5: 110 mg / H2 / 10 percent Pd-C / ethyl acetate / 5 h
View Scheme
参考文献
Srivastava, Savitri D.; Srivastava, Santosh K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 57 - 58
反应条件
1: sodium veratrate / 180 °C / unter vermindertem Druck; anschliessendes Erwaermen mit aethanol. Kalilauge
2: potassium carbonate; acetone
View Scheme
参考文献
Rao et al.
Proceedings - Indian Academy of Sciences, Section A, 1949 , # 29 p. 72,75
反应条件
1: 2',4',6'-trihydroxyacetophenone With potassium carbonate in acetone
T=20°C; 0.166667 h;
2: 3-(methoxybenzoyl) chloride in acetone
24 h; Heating;
参考文献
Gao, Hong; Kawabata, Jun
Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 9 p. 1858 - 1864
反应条件
1.1: aq. potassium carbonate; tetrabutylammonium bromide / benzene
2.1: aq. potassium carbonate / 6 h
2.2: acetic acid / Heating
View Scheme
参考文献
Chen, Zhiwei; Hu, Yongzhou; Wu, Haohao; Jiang, Huidi
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 15 p. 3949 - 3952
反应条件
1: acetone; benzene; K2CO3
2: aq. NaOH solution; aqueous .K2S2O8 / anschlissendes Erwaermen mit Na2SO3 und wss.HCl
View Scheme
参考文献
Sastri; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1946 , vol. 23, p. 262,266
反应条件
sodium methylate in methanol
12 h; Reflux;
参考文献
Mueller, Hans; Paul, Michael; Hartmann, David; Huch, Volker; Blaesius, Dagmar; Koeberle, Andreas; Werz, Oliver; Jauch, Johann
Angewandte Chemie - International Edition, 2010 , vol. 49, # 11 p. 2045 - 2049
反应条件
sodium methylate in methanol
7 h; Heating;
参考文献
Nakagawa-Goto, Kyoko; Wu, Jiu-Hong; Lee, Kuo-Hsiung
Synthetic Communications, 2005 , vol. 35, # 13 p. 1735 - 1739
反应条件
1: sodium-<2-methoxy benzoate / 180 °C / unter vermindertem Druck und kurzem Erwaermen des Reaktionsprodukts mit wss.-aethanol. Alkalilauge
2: aqueous sodium carbonate-solution
3: acetone; potassium carbonate
4: benzene; aluminium chloride
View Scheme
参考文献
Gupta; Seshadri
Proceedings - Indian Academy of Sciences, Section A, 1953 , # 37 p. 611,614
反应条件
1: potassium carbonate / acetone
2: potassium hydroxide / ethanol
3: hydrogenchloride / methanol; water / 0.5 h / Reflux
View Scheme
参考文献
Sui, Xin; Quan, Ying-Chun; Chang, Yue; Zhang, Rui-Peng; Xu, Yin-Feng; Guan, Li-Ping
Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1290 - 1296
反应条件
2: (KO3S)2NO, aq. NaOH
View Scheme
参考文献
Cavell,B.D.; MacMillan,J.
Journal of the Chemical Society [Section] C: Organic, 1967 , vol. <C>, p. 310 - 313
