反应条件
1: dimethylformaldehyde dimethyl acetal With acetyl chloride; zinc dibromide in dichloromethane
T=20 - 30°C; 3.5 h;
2: 2',4',6'-trihydroxyacetophenone With N-ethyl-N,N-diisopropylamine in dichloromethane
T=5 - 10°C;
参考文献
Brasca, Maria Gabriella; Mantegani, Sergio; Amboldi, Nadia; Bindi, Simona; Caronni, Dannica; Casale, Elena; Ceccarelli, Walter; Colombo, Nicoletta; De Ponti, Anna; Donati, Daniele; Ermoli, Antonella; Fachin, Gabriele; Felder, Eduard R.; Ferguson, Ronald D.; Fiorelli, Claudio; Guanci, Marco; Isacchi, Antonella; Pesenti, Enrico; Polucci, Paolo; Riceputi, Laura; Sola, Francesco; Visco, Carlo; Zuccotto, Fabio; Fogliatto, Gianpaolo
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 22 p. 7047 - 7063
