5,6-二甲氧基-2-(4-吡啶基)亚甲基-1-茚酮合成路线 （共 4 条）
反应条件
potassium hydroxide in water T=25 - 30°C; 3 h; Product distribution / selectivity;
参考文献
PIRAMAL HEALTHCARE LIMITED; GURUSAMY, Renugadevi; ROY, Mita; SHANMUGANATHAN, Ramasubramanian; JAGTAP, Ashutosh; HARIHARAN, Sivaramakrishnan; MISHRA, Sushil, Kumar; WANKHEDE, Karuna
Patent: WO2012/131540 A1, 2012 ;
Location in patent: Page/Page column 16 ;
反应条件
potassium tert-butylate in dimethyl sulfoxide T=15 - 20°C; Darzens condensation; Inert atmosphere;
参考文献
Dubey, Shailendra Kumar; Kharbanda, Manita; Dubey, Sushil Kumar; Mathela, Chandra Shekhar
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1157 - 1160
反应条件
n-butyllithium in tetrahydrofuran T=-78°C; Darzens condensation; Inert atmosphere;
参考文献
Dubey, Shailendra Kumar; Kharbanda, Manita; Dubey, Sushil Kumar; Mathela, Chandra Shekhar
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 9 p. 1157 - 1160
反应条件
hydrogen; platinum(IV) oxide in acetic acid T=80°C; P=760.051 Torr; 6 h;
参考文献
TIAN JIN HEMAY BIO-TECH CO., LTD
Patent: US2007/72905 A1, 2007 ;
Location in patent: Page/Page column 5 ;
