1,4-二羟基-2-甲基萘合成路线 （共 60 条）
反应条件
1,4-dioxane; trichloroacetic acid T=84°C; Schuetteln des Reaktionsprodukts in Aether und Petrolaether mit Ag2O und MgSO4;
参考文献
Fieser
Journal of the American Chemical Society, 1939 , vol. 61, p. 2559,3467, 3474
反应条件
1: NaOH / methanol
2: phenyliododiacetate; trimethylsilyl chloride / CH2Cl2
3: aq. ceric ammonium nitrate / acetonitrile
View Scheme
参考文献
Jung, Young-Sik; Joe, Bo-Young; Cho, Sung Ju; Konishi, Yasuo
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1125 - 1129
反应条件
pyridine
T=110 - 120°C;
参考文献
Ansbacher; Fernholz; Dolliver
Journal of the American Chemical Society, 1940 , vol. 62, p. 155,156
参考文献
Sah
Recueil des Travaux Chimiques des Pays-Bas, 1940 , vol. 59, p. 1029,1034
反应条件
1.) ether, 15 h, 0 deg C; Multistep reaction. Further byproducts given;
参考文献
Laatsch, Hartmut
Liebigs Annalen der Chemie, 1984 , # 7 p. 1367 - 1381
反应条件
1.) ether, 15 h, 0 deg C; Multistep reaction. Further byproducts given;
参考文献
Laatsch, Hartmut
Liebigs Annalen der Chemie, 1984 , # 7 p. 1367 - 1381
反应条件
boron trifluoride; zinc(II) chloride
anschliessend Behandeln mit Ag2O;
参考文献
Isler et al.
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1953 , vol. 295, p. 290,307
Helvetica Chimica Acta, 1958 , vol. 41, p. 786,803
反应条件
1: oxygen / 1,4-dioxane; water / 6 h / 20 °C
2: H4SiW12O40 / 48 h / 20 °C
3: potassium hydroxide / methanol / 6 h / 20 °C
View Scheme
参考文献
Hadjila, Dokari; Mohamed, Hammadi
Asian Journal of Chemistry, 2013 , vol. 25, # 11 p. 6112 - 6116
反应条件
sodium methylate in methanol; isopropyl alcohol
T=63°C; 0.5 h;
参考文献
Ito, Tatsuya; Ikemoto, Tomomi; Yamano, Toru; Mizuno, Yukio; Tomimatsu, Kiminori
Tetrahedron Asymmetry, 2003 , vol. 14, # 22 p. 3525 - 3531
反应条件
sodium hydroxide; stannous chloride; dimethyl sulfate in hydrogenchloride; ethanol; water
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5804601 A1, 1998 ;
