2-氨基-4-苯基噻吩-3-羧酸乙酯合成路线 （共 25 条）
反应条件
hydrogenchloride in water 1.08333 h; Microwave irradiation;
参考文献
Jain, Kishor S.; Bariwal, Jitender B.; Phoujdar, Manisha S.; Nagras, Madhuri A.; Amrutkar, Rakesh D.; Munde, Manoj K.; Tamboli, Riyaj S.; Khedkar, Samrat A.; Khiste, Rahul H.; Vidyasagar, Nikhil C.; Dabholkar, Vinit V.; Kathiravan
Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 2 p. 178 - 185
反应条件
1: 83 percent / HCl gaseous / Ambient temperature 2: 77 percent / 2percent NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Pech; Bohm
Pharmazie, 1989 , vol. 44, # 11 p. 790 - 791
反应条件
1: 55 percent / HClgas / dioxane / 5 h 2: 43 percent / POCl3 / 12 h / Heating View Scheme
参考文献
Shishoo, C. J.; Devani, M. B.; Karvekar, M. D.; Ullas, G. V.; Ananthan, S.; et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. <B> 21, # 7 p. 666 - 668
反应条件
in ethanol 16 h; Heating;
参考文献
Cannito, A.; Perrissin, M.; Luu-Duc, C.; Huguet, F.; Gaultier, C.; Narcisse, G.
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 8 p. 635 - 639
反应条件
1: pyridine / 50 °C 2: MaONa / methanol / 20 °C View Scheme
参考文献
Duval, Eric; Case, April; Stein, Ross L.; Cuny, Gregory D.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1885 - 1889
反应条件
1: 63 percent / 4 h / Heating 2: 74 percent / PCl5, POCl3 / 3 h / Heating View Scheme
参考文献
Hozien; Atta; Hassan; Abdel-Wahab; Ahmed
Synthetic Communications, 1996 , vol. 26, # 20 p. 3733 - 3755
反应条件
hydrogenchloride in chloroform 2 h;
参考文献
Perrissin; Favre; Luu Duc; Huguet; Gaultier; Narcisse
European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 453 - 456
反应条件
potassium hydroxide
5 h; Heating;
参考文献
Offermann; Eger; Roth
Archiv der Pharmazie, 1981 , vol. 314, # 2 p. 168 - 175
参考文献
Perrissin; Duc; Narcisse; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 563 - 565
参考文献
Perrissin; Duc; Narcisse; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 6 p. 563 - 565
