5-(4-氟-苯基)-噻唑-4-羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide in ethanol
6 h; Reflux;
参考文献
Nagashima, Shinya; Matsushima, Yuji; Hamaguchi, Hisao; Nagata, Hiroshi; Kontani, Toru; Moritomo, Ayako; Koshika, Tadatsura; Takeuchi, Makoto
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 13 p. 3478 - 3487
反应条件
1: sodium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; 1,4-dioxane / 5 h / 90 °C
2: sodium hydroxide / ethanol / 6 h / |Reflux
View Scheme
参考文献
Nagashima, Shinya; Matsushima, Yuji; Hamaguchi, Hisao; Nagata, Hiroshi; Kontani, Toru; Moritomo, Ayako; Koshika, Tadatsura; Takeuchi, Makoto
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 13 p. 3478 - 3487
