1,2,3,4-四氢异喹啉-2-胺合成路线 （共 4 条）
反应条件
T=195 - 200°C; 0.5 h;
参考文献
Viswanathan, V.; Kaul, C. L.; Grewal, R. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 9 p. 776 - 779
反应条件
titanium tetrachloride; magnesium in diethyl ether; 1,2-dichloro-ethane
0.5 h; Ambient temperature;
参考文献
Landriani; Barlocco; Pinna; Demontis; Miele; Enrico; Anania
Farmaco, 1989 , vol. 44, # 11 p. 1059 - 1068
反应条件
sulfuric acid; sodium nitrite
Erwaermen des Reaktionsprodukts mit Lithiumalanat in Aether;
参考文献
Biel et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 2805,2810, 2813
反应条件
1: 94 percent / NaNO3 / H2O; acetic acid / 2 h / Ambient temperature
2: 86 percent / TiCl4, Mg / 1,2-dichloro-ethane; diethyl ether / 0.5 h / Ambient temperature
View Scheme
参考文献
Landriani; Barlocco; Pinna; Demontis; Miele; Enrico; Anania
Farmaco, 1989 , vol. 44, # 11 p. 1059 - 1068
