反应条件
1: 1) thionylchloride 2) NH3 / 1) benzene, reflux, 45 min 2) H2O 2: phosphoryl chloride / 5 h / 100 °C 3: 98.5 percent / NaOH, H2O2 / 1) 40-60 deg C, 1 h 2) reflux, 4h 4: 76 percent / NaOH, Br2 / H2O / 0.75 h / 70 °C 5: 1) conc. HCl, NaNO2, 2) CuCl2/conc. HCl / 1) 10 deg C, 5 min 2) 5 deg C, 30 min, then RT, 1 h 6: 99 percent / HCl / ethanol / 1 h / Heating 7: 95 percent / polyphosphoric acid / 2.5 h / 120 °C 8: 65 percent / methanol 9: DDQ / dioxane View Scheme
参考文献
Rajamanickam, P.; Shanmugam, P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, p. 910 - 913
