9-甲基呋喃并[2,3-b]喹啉-4(9H)-酮合成路线 （共 15 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
Elimination; 0.166667 h;
参考文献
Pirrung, Michael C.; Blume, Florian
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3642 - 3649
反应条件
potassium hydrogensulfate in 1,4-dioxane
Heating;
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
反应条件
1: 90 percent / mesyl azide; triethylamine / ethanol / 12 h / 20 °C
2: 12 percent / rhodium(II) pivalate / fluorobenzene / 55 °C
3: 61 percent / TBAF / tetrahydrofuran / 0.17 h
View Scheme
参考文献
Pirrung, Michael C.; Blume, Florian
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3642 - 3649
反应条件
1: 70 percent / acetic acid / 5 h / Heating
2: 90 percent / mesyl azide; triethylamine / ethanol / 12 h / 20 °C
3: 12 percent / rhodium(II) pivalate / fluorobenzene / 55 °C
4: 61 percent / TBAF / tetrahydrofuran / 0.17 h
View Scheme
参考文献
Pirrung, Michael C.; Blume, Florian
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3642 - 3649
反应条件
1: 12 percent / rhodium(II) pivalate / fluorobenzene / 55 °C
2: 61 percent / TBAF / tetrahydrofuran / 0.17 h
View Scheme
参考文献
Pirrung, Michael C.; Blume, Florian
Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3642 - 3649
反应条件
1: tetrahydrofuran; hexane / 1.) r.t., overnight, 2.) reflux, 2 h
2: 85 percent / diphenyl ether / 0.17 h / 245 - 255 °C
3: 66 percent / K2CO3 / dimethylformamide / 1 h / 30 °C
4: 72 percent / NaBH4, 2 N NaOH / methanol / 3 h / Ambient temperature
5: 74 percent / KHSO4 / dioxane / Heating
View Scheme
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
反应条件
1: 85 percent / diphenyl ether / 0.17 h / 245 - 255 °C
2: 66 percent / K2CO3 / dimethylformamide / 1 h / 30 °C
3: 72 percent / NaBH4, 2 N NaOH / methanol / 3 h / Ambient temperature
4: 74 percent / KHSO4 / dioxane / Heating
View Scheme
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
反应条件
1: 72 percent / NaBH4, 2 N NaOH / methanol / 3 h / Ambient temperature
2: 74 percent / KHSO4 / dioxane / Heating
View Scheme
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
反应条件
1: 66 percent / K2CO3 / dimethylformamide / 1 h / 30 °C
2: 72 percent / NaBH4, 2 N NaOH / methanol / 3 h / Ambient temperature
3: 74 percent / KHSO4 / dioxane / Heating
View Scheme
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
反应条件
1: tetrahydrofuran; hexane / 1.) r.t., overnight, 2.) reflux, 2 h
2: 85 percent / diphenyl ether / 0.17 h / 245 - 255 °C
3: 66 percent / K2CO3 / dimethylformamide / 1 h / 30 °C
4: 72 percent / NaBH4, 2 N NaOH / methanol / 3 h / Ambient temperature
5: 74 percent / KHSO4 / dioxane / Heating
View Scheme
参考文献
Kuo; Huang; Cheng; Ling; Wu; Ishii; Nakamura
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 4 p. 955 - 963
