顺-4-环己烯-1,2-二羧酸二乙酯合成路线 （共 11 条）
反应条件
1: 84 percent / 50percent NaOH, Et3PhCH2NCl / 6 h / 40 - 50 °C
2: 66 percent / LiAlH4 / diethyl ether / 8 h / Ambient temperature
3: 18 percent / SOCl2 / pyridine / 1.) 0 deg C, 30 min; 2.) reflux, 20 min
4: 45 percent / KO-t-Bu / tetrahydrofuran / 1.5 h
5: 60 percent / CH2Cl2 / 2.5 h / Heating
View Scheme
参考文献
Davalian, Dariush; Garratt, Peter J.; Koller, Wolfgang; Mansuri, Muzammil M.
Journal of Organic Chemistry, 1980 , vol. 45, # 21 p. 4183 - 4193
