3',4',7-三羟基异黄酮合成路线 （共 19 条）
反应条件
1: With boron tribromide in dichloromethane T=0 - 20°C; 6 h; 2: With water in dichloromethane T=0°C;
参考文献
Matin, Azadeh; Gavande, Navnath; Kim, Moon S.; Yang, Nancy X.; Salam, Noeris K.; Hanrahan, Jane R.; Roubin, Rebecca H.; Hibbs, David E.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 21 p. 6835 - 6850
反应条件
NADPH disodium salt; β-D-galactose in dimethyl sulfoxide T=30°C; 72 h; Microbiological reaction;
参考文献
Chemler, Joseph A.; Lim, Chin Giaw; Daiss, John L.; Koffas, Mattheos A.G.
Chemistry and Biology, 2010 , vol. 17, # 4 p. 392 - 401
反应条件
1: T=50°C; 0.166667 h; 2: With methanesulfonyl chloride in N,N-dimethyl-formamide T=80°C; 0.5 h;
参考文献
Goto, Hideyuki; Terao, Yoshiyasu; Akai, Shuji
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 4 p. 346 - 360
反应条件
1: 92.1 percent / 50percent aq. KOH / ethanol / 24 h / Ambient temperature 2: thallium nitrate / CHCl3 / Ambient temperature 3: H2, triethylamine / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature 4: 5percent HCl / methanol / 2 h / Heating View Scheme
参考文献
Nishiyama, Kiyotoshi; Esaki, Sachiko; Deguchi, Ikuko; Sugiyama, Naoko; Kamiya, Shintaro
Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 1 p. 107 - 114
反应条件
1: thallium nitrate / CHCl3 / Ambient temperature 2: H2, triethylamine / 10percent Pd/C / ethyl acetate / 760 Torr / Ambient temperature 3: 5percent HCl / methanol / 2 h / Heating View Scheme
参考文献
Nishiyama, Kiyotoshi; Esaki, Sachiko; Deguchi, Ikuko; Sugiyama, Naoko; Kamiya, Shintaro
Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 1 p. 107 - 114
反应条件
boron tribromide in dichloromethane 1 h; Ambient temperature;
参考文献
Kirkiacharian, B. Serge; Brion, Jean-Daniel; Gomis, Michel; Reynaud, Pierre
Heterocycles, 1980 , vol. 14, # 12 p. 1929 - 1934
反应条件
2: 1.) N2B6, 2.) pyridinum dichromate / 2.) methylene chloride, 0 deg C, 3 h 3: 40 percent / 2,3-dichloro 5,6-dicyano benzoquinone (D.D.Q.) / benzene 4: boron tribromide / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Kirkiacharian, B. Serge; Brion, Jean-Daniel; Gomis, Michel; Reynaud, Pierre
Heterocycles, 1980 , vol. 14, # 12 p. 1929 - 1934
反应条件
2: 1.) N2B6, 2.) pyridinum dichromate / 2.) methylene chloride, 0 deg C, 3 h 3: 40 percent / 2,3-dichloro 5,6-dicyano benzoquinone (D.D.Q.) / benzene 4: boron tribromide / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Kirkiacharian, B. Serge; Brion, Jean-Daniel; Gomis, Michel; Reynaud, Pierre
Heterocycles, 1980 , vol. 14, # 12 p. 1929 - 1934
反应条件
1: 1.) N2B6, 2.) pyridinum dichromate / 2.) methylene chloride, 0 deg C, 3 h 2: 40 percent / 2,3-dichloro 5,6-dicyano benzoquinone (D.D.Q.) / benzene 3: boron tribromide / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Kirkiacharian, B. Serge; Brion, Jean-Daniel; Gomis, Michel; Reynaud, Pierre
Heterocycles, 1980 , vol. 14, # 12 p. 1929 - 1934
反应条件
1: 40 percent / 2,3-dichloro 5,6-dicyano benzoquinone (D.D.Q.) / benzene 2: boron tribromide / CH2Cl2 / 1 h / Ambient temperature View Scheme
参考文献
Kirkiacharian, B. Serge; Brion, Jean-Daniel; Gomis, Michel; Reynaud, Pierre
Heterocycles, 1980 , vol. 14, # 12 p. 1929 - 1934
