1-苯基-1,3-丙二醇合成路线 （共 84 条）
反应条件
potassium hydroxide in butan-1-ol
参考文献
Mamedov,S. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, p. 1446 - 1451,1411 - 1415
反应条件
potassium hydroxide in methanol; diethyl ether
3 h;
参考文献
Merkley, Nadine; Warkentin, John
Canadian Journal of Chemistry, 2002 , vol. 80, # 9 p. 1187 - 1195
反应条件
in tetrahydrofuran
T=20°C; 3 h; optical yield given as percent ee;
参考文献
Bertolini, Ferruccio; Crotti, Stefano; Di Bussolo, Valeria; Macchia, Franco; Pineschi, Mauro
Journal of Organic Chemistry, 2008 , vol. 73, # 22 p. 8998 - 9007
反应条件
sodium tetrahydroborate in ethanol
参考文献
Kiyooka, Syun-ichi; Kaneko, Yuichi; Komura, Misako; Matsuo, Hidehito; Nakano, Masahito
Journal of Organic Chemistry, 1991 , vol. 56, # 7 p. 2276 - 2278
反应条件
dihydrogen peroxide; sodium hydrogencarbonate in tetrahydrofuran; methanol
18 h; Heating; Yield given;
参考文献
Klos, Andrew M.; Heintzelman, Geoffrey R.; Weinreb, Steven M.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3758 - 3761
反应条件
1: 65 percent / tetrahydrofuran / 15 h / 0 °C
2: KHF2, TFA / CHCl3 / 18 h / Ambient temperature
3: NaHCO3, H2O2 / tetrahydrofuran; methanol / 18 h / Heating
View Scheme
参考文献
Klos, Andrew M.; Heintzelman, Geoffrey R.; Weinreb, Steven M.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3758 - 3761
反应条件
1: KHF2, TFA / CHCl3 / 18 h / Ambient temperature
2: NaHCO3, H2O2 / tetrahydrofuran; methanol / 18 h / Heating
View Scheme
参考文献
Klos, Andrew M.; Heintzelman, Geoffrey R.; Weinreb, Steven M.
Journal of Organic Chemistry, 1997 , vol. 62, # 11 p. 3758 - 3761
反应条件
1: tetrahydrofuran / 6 h / Heating
2: 79.5 percent / 1)Methanesulfonic acid,2) NaOH, 30percent H2O2 / tetrahydrofuran / 6 h / 65 °C
View Scheme
参考文献
Brown, Herbert C.; Kim, Suk-Choong
Journal of Organic Chemistry, 1984 , vol. 49, # 6 p. 1064 - 1071
反应条件
1: 80percent AcOH / H2O / 0.17 h / Ambient temperature
2: NaBH4 / ethanol
View Scheme
参考文献
Kiyooka, Syun-ichi; Kaneko, Yuichi; Komura, Misako; Matsuo, Hidehito; Nakano, Masahito
Journal of Organic Chemistry, 1991 , vol. 56, # 7 p. 2276 - 2278
反应条件
sodium tetrahydroborate in methanol
T=10°C;
参考文献
Borowiecki, Pawel; Bretner, Maria
Tetrahedron Asymmetry, 2013 , vol. 24, # 15-16 p. 925 - 936
