甲基 4-(吲哚-2-基)苯甲酸合成路线 （共 12 条）
反应条件
palladium diacetate; (S)-(-)-2-methyl-2-propanesulfinamide; caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=100°C; 15 h; Inert atmosphere;
参考文献
Prakash, Anjanappa; Dibakar, Mullick; Selvakumar, Kumaravel; Ruckmani, Kandasamy; Sivakumar, Manickam
Tetrahedron Letters, 2011 , vol. 52, # 43 p. 5625 - 5628
反应条件
potassium carbonate; L-proline; copper(I) bromide in dimethyl sulfoxide T=100°C; 3 h; Inert atmosphere;
参考文献
Ponpandian, Thanasekaran; Muthusubramanian, Shanmugam
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4248 - 4252
反应条件
potassium phosphate; Cu[(phen)(PPh3)2]NO2 in toluene T=110°C; 3 h;
参考文献
Cacchi, Sandro; Fabrizi, Giancarlo; Parisi, Luca M.
Organic Letters, 2003 , vol. 5, # 21 p. 3843 - 3846
反应条件
copper(l) iodide; potassium carbonate; L-proline in N,N-dimethyl-formamide T=80°C; 24 h;
参考文献
Liu, Feng; Ma, Dawei
Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4844 - 4850
反应条件
1: With copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in toluene T=105°C; 24 h; Inert atmosphere; 2: With trifluoroacetic acid in dichloromethane T=23°C; 2 h; Inert atmosphere;
参考文献
Ackermann, Lutz; Barfuesser, Sebastian; Potukuchi, Harish K.
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 7-8 p. 1064 - 1072
反应条件
Au/Carbon G-60 catalyst in toluene T=90°C; 48 h; Inert atmosphereSchlenk technique;
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
potassium phosphate; copper(l) iodide; triphenylphosphine in 1,4-dioxane T=110°C; 24 h;
参考文献
Cacchi, Sandro; Fabrizi, Giancarlo; Parisi, Luca M.
Organic Letters, 2003 , vol. 5, # 21 p. 3843 - 3846
反应条件
[Rh(coe)2Cl]2; CsO2CCMe3; tris(4-trifluoromethylphenyl)phosphine in 1,4-dioxane 72 h; Inert atmosphereReflux; regioselective reaction;
参考文献
Bremner, John B.; Kelso, Michael J.
Synthetic Communications, 2010 , vol. 40, # 23 p. 3561 - 3568
反应条件
titanium(III) chloride in hydrogenchloride; water Inert atmosphere; regioselective reaction;
参考文献
Wetzel, Alexander; Pratsch, Gerald; Kolb, Roman; Heinrich, Markus R.
Chemistry - A European Journal, 2010 , vol. 16, # 8 p. 2547 - 2556
反应条件
1: sulfuric acid / 48 h / Reflux 2: [Rh(coe)2Cl]2; CsO2CCMe3; tris(4-trifluoromethylphenyl)phosphine / 1,4-dioxane / 72 h / Inert atmosphere; Reflux View Scheme
参考文献
Bremner, John B.; Kelso, Michael J.
Synthetic Communications, 2010 , vol. 40, # 23 p. 3561 - 3568
