N,N'-环己烷双马来亚酰胺合成路线 (共 6 条)
反应条件
1: in N,N-dimethyl-formamide T=90°C; 0.5 h; 2: With [Ni(O2CCH3)2]*4H2O; acetic anhydride; triethylamine in N,N-dimethyl-formamide T=90°C; 0.5 h;
参考文献
Asadirad, Amir Mahmoud; Boutault, Stephanie; Erno, Zach; Branda, Neil R.
Journal of the American Chemical Society, 2014 , vol. 136, # 8 p. 3024 - 3027
反应条件
sodium hydrogencarbonate in tetrahydrofuran 3 h; Ambient temperature;
参考文献
Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 9 p. 1563 - 1572
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 40 °C / Inert atmosphere 2: toluene / Reflux View Scheme
参考文献
Patel, Dinesh G.; Graham, Kenneth R.; Reynolds, John R.
Journal of Materials Chemistry, 2012 , vol. 22, # 7 p. 3004 - 3014
反应条件
1: acetone / 1 h 2: sodium acetate; acetic anhydride; triethylamine / acetone / 3 h / Reflux View Scheme
参考文献
Dispinar, Tugba; Van Camp, Wim; De Cock, Liesbeth J.; De Geest, Bruno G.; Du Prez, Filip E.
Macromolecular Bioscience, 2012 , vol. 12, # 3 p. 383 - 394
反应条件
sodium acetate; acetic anhydride; triethylamine in acetone 3 h; Reflux;
参考文献
Dispinar, Tugba; Van Camp, Wim; De Cock, Liesbeth J.; De Geest, Bruno G.; Du Prez, Filip E.
Macromolecular Bioscience, 2012 , vol. 12, # 3 p. 383 - 394
反应条件
acetic anhydride in water; acetone
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4154737 A1, 1979 ;