1,2-二氢-5-苯基吡唑-3-酮合成路线 （共 6 条）
反应条件
lead(IV) acetate 0.25 h;
参考文献
Myrboh, B.; Ila, H.; Junjappa, H.
Synthesis, 1982 , # 12 p. 1100 - 1102
反应条件
4-toluenesulfonyl azide; triethylamine in methanol 3 h; Ambient temperature; Yield given;
参考文献
Padwa, Albert; Woolhouse, Anthony D.; Blount, John J.
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1069 - 1074
反应条件
1.1: POCl3 / Heating
1.2: Et3N / tetrahydrofuran / 20 °C
2.1: Na2CO3 / methanol / Heating
3.1: 44 percent / NaOH / methanol / 50 °C
4.1: 99 percent / HCl / dioxane
View Scheme
参考文献
Akritopoulou-Zanze, Irini; Darczak, Daria; Sarris, Kathy; Phelan, Kathleen M.; Huth, Jeffrey R.; Song, Danying; Johnson, Eric F.; Jia, Yong; Djuric, Stevan W.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 1 p. 96 - 99
反应条件
hydrogenchloride; 4-toluenesulfonyl azide; triethylamine in N,N-dimethyl-formamide
0.25 h;
参考文献
Umrigar, Pesi; Griffin, Gary W.; Ege, Seyhan N.; Adams, Alan D.; Das, Paritosh K.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2456 - 2463
反应条件
4-toluenesulfonyl azide; triethylamine in methanol
3 h; Ambient temperature; Yield given;
参考文献
Padwa, Albert; Woolhouse, Anthony D.; Blount, John J.
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1069 - 1074
参考文献
Tomasik, Danuta; Tomasik, Piotr; Abramovitch, Rudolph A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1539 - 1543
