2-甲基-4-羰基-2-环己烯-1-羧酸乙酯合成路线 （共 41 条）
反应条件
1: diethyl ether / 0 °C 2: thermal or acidocatalyzed dehydration View Scheme
参考文献
Gesson, J.P.; Jacquesy, J.C.; Renoux, B.
Tetrahedron Letters, 1983 , vol. 24, # 27 p. 2757 - 2760
反应条件
camphor-10-sulfonic acid 1.) ether, hexane, THF, 0 deg C, 30 min; 2.) benzene, reflux, 12 h; Yield given. Multistep reaction;
参考文献
Kawasaki, Motoji; Matsuda, Fuyuhiko; Terashima, Shiro
Tetrahedron, 1988 , vol. 44, # 18 p. 5727 - 5744
反应条件
Dowex-50 in water 12 h; Heating;
参考文献
Basu, Manas K.; Sarkar, Dipak C.; Ranu, Brindaban C.
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 627 - 632
反应条件
unter CO2-Entwicklung;
参考文献
Hagemann
Chemische Berichte, 1893 , vol. 26, p. 884
反应条件
toluene-4-sulfonic acid in benzene 12 h; Heating;
参考文献
Fulmer, T. D.; Bryson, T. A.
Journal of Organic Chemistry, 1989 , vol. 54, p. 3496 - 3500
反应条件
1: 62 percent / t-BuOK / 2-methyl-propan-2-ol / 16 h / Heating 2: 71 percent / KOH / aq. ethanol / 14 h / Heating View Scheme
参考文献
Pal, Sitaram; Mukhopadhyaya, Jayanta K.; Ghatak, Usha Ranjan
Journal of Organic Chemistry, 1994 , vol. 59, # 10 p. 2687 - 2694
反应条件
1: sodium amide; liquid ammonia / Erwaermen des vom Ammoniak befreiten Reaktionsgemisches mit Methyljodid in Aether 2: aqueous ethanol KOH 3: methanol; palladium / Hydrogenation View Scheme
参考文献
Cornubert; Maurel
Bulletin de la Societe Chimique de France, 1931 , vol. <4> 49, p. 1498,1512
反应条件
1: NaH / dimethylformamide
2: KOH / ethanol
View Scheme
参考文献
McAndrew,B.A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 1837 - 1846
反应条件
(i) NaBH4, EtOH, (ii) aq. NaOH, (iii) H2SO4; Multistep reaction;
参考文献
Ruettimann,A. et al.
Helvetica Chimica Acta, 1975 , vol. 58, p. 1450 - 1455
反应条件
1: sodium ethylate / durch Verseifung mit alkoh. Kalilauge
2: bei der Destillation
View Scheme
参考文献
Bannard; Leitch
Canadian Journal of Chemistry, 1956 , vol. 34, p. 1464,1467
