1.1: triphenylphosphine / dichloromethane / 0.33 h / 0 °C / |Inert atmosphere
1.2: 1.5 h / 0 °C / |Inert atmosphere
2.1: n-butyllithium / hexane; diethyl ether / -78 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Dixon, Luke I.; Carroll, Michael A.; Gregson, Thomas J.; Ellames, George J.; Harrington, Ross W.; Clegg, William
European Journal of Organic Chemistry, 2013 , # 12 p. 2334 - 2345
1.1: tetrahydrofuran / 12 h / 20 °C
2.1: sodium ethanolate / ethanol / 12 h
2.2: 12 h
View Scheme
参考文献
Zhang, Wei; Benmohamed, Radhia; Arvanites, Anthony C.; Morimoto, Richard I.; Ferrante, Robert J.; Kirsch, Donald R.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 1029 - 1045