1,5-二苯基-1H-1,2,3-噻唑合成路线 （共 27 条）
反应条件
sodium azide; acetic acid; sodium nitrite in water
15 h; Reflux; regioselective reaction;
参考文献
Dey, Santu; Pathak, Tanmaya
RSC Advances, 2014 , vol. 4, # 18 p. 9275 - 9278
反应条件
potassium permanganate; tetrabutyl-ammonium chloride in water; benzene
4 h; Heating;
参考文献
Kadaba, Pankaja K.
Journal fuer Praktische Chemie (Leipzig), 1982 , vol. 324, # 5 p. 857 - 864
反应条件
1: trimethylsilylazide / methanol / 8 h / 20 °C
2: copper diacetate; caesium carbonate / N,N-dimethyl acetamide; methanol / 20 - 150 °C
3: zinc trifluoromethanesulfonate / toluene / 0.5 h / 150 °C / |Microwave irradiation
View Scheme
参考文献
El Kaim, Laurent; Grimaud, Laurence; Pravin, Patil
European Journal of Organic Chemistry, 2013 , # 22 p. 4752 - 4755
反应条件
in water
10 h; Reflux; regioselective reaction;
参考文献
Dey, Santu; Datta, Dhrubajyoti; Pathak, Tanmaya
Synlett, 2011 , # 17 p. 2521 - 2524
反应条件
1: copper diacetate; caesium carbonate / N,N-dimethyl acetamide; methanol / 20 - 150 °C
2: zinc trifluoromethanesulfonate / toluene / 0.5 h / 150 °C / |Microwave irradiation
View Scheme
参考文献
El Kaim, Laurent; Grimaud, Laurence; Pravin, Patil
European Journal of Organic Chemistry, 2013 , # 22 p. 4752 - 4755
反应条件
in ethanol
36 h; Heating; Yield given;
参考文献
Abu-Orabi, Sultan T.; Atfah, M. Adnan; Jibril, Ibrahim; Mari'i, Fakhri M.; Ali, Amer Al-Sheikh
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1461 - 1468
反应条件
1: tert.-butylnitrite; trimethylsilylazide / acetonitrile / 1 h / 20 °C / |Inert atmosphere; |Schlenk technique
2: {Y[N(SiMe3)2]2(μ-Cl)(THF)}2 / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere; |Schlenk technique
View Scheme
参考文献
Hong, Longcheng; Lin, Weijia; Zhang, Fangjun; Liu, Ruiting; Zhou, Xigeng
Chemical Communications, 2013 , vol. 49, # 49 p. 5589 - 5591
反应条件
1.1: trimethylammonioacetate / N,N-dimethyl-formamide / 1 h / 90 °C
1.2: 5 h / 90 °C
2.1: MMPP*6H2O / methanol / 6 h / 20 °C
3.1: pyridine; methanesulfonyl chloride / 0 - 4 °C
4.1: water / 10 h / Reflux
View Scheme
参考文献
Dey, Santu; Datta, Dhrubajyoti; Pathak, Tanmaya
Synlett, 2011 , # 17 p. 2521 - 2524
反应条件
1: pyridine; methanesulfonyl chloride / 0 - 4 °C
2: water / 10 h / Reflux
View Scheme
参考文献
Dey, Santu; Datta, Dhrubajyoti; Pathak, Tanmaya
Synlett, 2011 , # 17 p. 2521 - 2524
反应条件
1: MMPP*6H2O / methanol / 6 h / 20 °C
2: pyridine; methanesulfonyl chloride / 0 - 4 °C
3: water / 10 h / Reflux
View Scheme
参考文献
Dey, Santu; Datta, Dhrubajyoti; Pathak, Tanmaya
Synlett, 2011 , # 17 p. 2521 - 2524
