2,2’-二甲氧基联苯合成路线 （共 133 条）
反应条件
1: With magnesium in tetrahydrofuran Grignard Reaction; Inert atmosphereReflux; 2: With dilithium tetrachlorocuprate(II); oxygen in tetrahydrofuran T=20°C; 2 h;
参考文献
Hua, Si-Kai; Hu, Qiu-Peng; Ren, Jiangmeng; Zeng, Bu-Bing
Synthesis (Germany), 2013 , vol. 45, # 4 art. no. SS-2012-H0751-OP, p. 518 - 526
反应条件
[C12mim][CuCl2]; copper; zinc T=90°C; 4 h;
参考文献
Hu, Yu-Lin; Li, Fu; Gu, Guo-Liang; Lu, Ming
Catalysis Letters, 2011 , vol. 141, # 3 p. 467 - 473
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran; N,N-dimethyl-formamide T=90°C; 12 h;
参考文献
Seganish, W. Michael; Mowery, Molly E.; Riggleman, Shaundra; DeShong, Philip
Tetrahedron, 2005 , vol. 61, # 8 p. 2117 - 2121
反应条件
anhydrous iron chloride; 1,2-dichloro-ethane in tetrahydrofuran T=0°C; 0.0833333 h; Ionic liquidInert atmosphere;
参考文献
Kude, Keisuke; Hayase, Shuichi; Kawatsura, Motoi; Itoh, Toshiyuki
Heteroatom Chemistry, 2011 , vol. 22, # 3-4 p. 397 - 404
反应条件
potassium carbonate; palladium dichloride in water; N,N-dimethyl-formamide T=20°C; Suzuki cross-coupling reaction; 0.166667 h;
参考文献
Liu, Chun; Ni, Qijian; Bao, Fanying; Qiu, Jieshan
Green Chemistry, 2011 , vol. 13, # 5 p. 1260 - 1266
反应条件
α-Bromo-benzeneacetic acid methyl ester; potassium fluoride; ((S)-2,2′-bis(diphenylphosphino)-1,1′-binaphthyl)PdCl2*2THF in 1,4-dioxane; water T=100°C;
参考文献
Lei, Aiwen; Zhang, Xumu
Tetrahedron Letters, 2002 , vol. 43, # 14 p. 2525 - 2528
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Delogu, Giovanna; Dettori, Maria Antonietta; Patti, Angela; Pedotti, Sonia; Forni, Alessandra; Casalone, Gianluigi
Tetrahedron Asymmetry, 2003 , vol. 14, # 16 p. 2467 - 2474
反应条件
palladium diacetate; N-ethyl-N,N-diisopropylamine in 1,4-dioxane; water T=110°C; Suzuki coupling; 1 h;
参考文献
Berezin, Andrey A.; Koutentis, Panayiotis A.
Tetrahedron, 2011 , vol. 67, # 22 p. 4069 - 4078
反应条件
iron(II) chloride in tetrachloromethane T=60°C; 3 h;
参考文献
Ding, Yiyuan; Song, Qingbao; Cheng, Kai; Qi, Chenze
Tetrahedron Letters, 2012 , vol. 53, # 46 p. 6269 - 6272,4
反应条件
1: 2,2'-dihydroxy-1,1'-biphenyl With potassium carbonate in acetone T=20°C; 0.166667 h; Inert atmosphere; 2: dimethyl sulfate in acetone T=20°C; 12 h; Inert atmosphere;
参考文献
Fernandes, Rodney A.; Mulay, Sandip V.
Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 7029 - 7032
